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Tight junctions are cell junctions that seal tissues. These junctions form protective and functional barriers.

  • The cell junction that is involved in creating a barrier between cells is the TIGHT junction.

  • The tight junctions are cell-cell adhesion structures implicated in cell polarity and signaling.

  • On the other hand, adherens junctions are cell junctions required for maintaining contact inhibition.

  • Finally, desmosomes are intercellular junctions that bind intermediate filaments of the cytoskeleton with cadherin proteins.

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